If you are receiving the Windows 10 update error 0x80070643 while you are trying to update your Windows 10 operating system, proceed with the steps that are given below to fix the issue.

Step 1: Fixing Windows Defender corrupted files

  • Press the Windows and R buttons together to launch the Run dialog box.
  • Type “cmd” in the Search section and hit the Enter key.
  • When the Command Prompt window appears, type “%ProgramFiles%\Windows Defender\MPCMDRUN.exe” -RemoveDefinitions -All. This process will remove the corrupted files.
  • Now, enter %ProgramFiles%\Windows Defender\MPCMDRUN.exe” -SignatureUpdate.
  • Once you receive a message stating that the signature update is complete, type %ProgramFiles%\Windows Defender\MPCMDRUN.exe” -SignatureUpdate -MMPC.
  • If you have recently removed any third-party Antivirus programs, make sure to delete the trace files from the installation folder. Then, restart your computer and checks the error Windows 10 update error 0x80070643.

Step 2: Run the Windows troubleshooter

  • Click the Search icon near the Start menu and type Troubleshoot.
  • In the Troubleshoot window, select the Windows Update section. Then, click the Run the troubleshooter option.
  • The troubleshooter scans for the issues Windows 10 update error 0x80070643 present on your system. Click the Apply this fix option in the Download and Install pending updates section.
  • Again, select ‘Apply this fix to repair the Windows Update database corruption.’
  • When the troubleshooting process is complete, restart your computer.
  • Go to the Windows Update section from Settings and click on the Check for Updates button.
  • If the error appears again, continue with the other steps.
Windows 10 update error 0x80070643

Step 3: Run SFC and DISM scans

  • Enter “cmd” in the Search section near Start. Then, right-click on Command Prompt and select the Run as administrator option.
  • Type “sfc /scannow” when the Command Prompt window appears and hit the Enter key.
  • If the SFC scan doesn’t solve the issue, run the DISM scan.
  • Open Command Prompt as an admin user, type “DISM /Online /Cleanup-Image /RestoreHealth,” and tap Enter.
  • Wait until the scan is complete and restart your computer and checks the Windows 10 update error 0x80070643.

Step 4: Start a clean boot

  • Press the Windows and R buttons together, and type “msconfig” in the Run dialog box that opens.
  • Select the Services tab and uncheck the Hide all Microsoft Services option. Then, click on the Disable all button.
  • Go to the Startup tab and select the Open Task Manager link.
  • Now, right-click on the first program and select Disable. Repeat the same process for all the running programs.
  • Exit Task Manager and click Apply in the System Configuration window.

Step 5: Restarting the Security Center Service

  • If the issue persists, open the Run dialog box and type “services.msc” in the Search section. Then, tap Enter.
  • When the Services window appears, locate Security Center and right-click on it. Then, select the Restart option.

Step 6: Disable .NET Framework

  • Press the Windows key and type Windows features. Click the Turn Windows features option.
  • Uncheck the boxes beside the Windows Communication Foundation HTTP Activation and Non-HTTP Activation options. Then, select the OK button in the Windows Features window to apply the settings.
  • Now, you can update your Windows operating system
  • Restart your computer to fix the issue Windows 10 update error 0x80070643.